Source: Astral Codex Ten
by Scott Alexander
“In 2021, I discussed tradeoff vs. failure models of psychiatric conditions, and said that most conditions were probably a mix of both. The new research seems to confirm this: the first genetic component of schizophrenia is a tradeoff: bad insofar as it gives you higher schizophrenia risk, good insofar as it gives you higher educational attainment. Most likely this has something to do with creativity or motivation. The second component is a failure: bad in every way, with no compensating advantage. Most likely this is detrimental mutations in genes for neurogenesis and synaptic pruning.” (03/26/26)
https://www.astralcodexten.com/p/how-natural-tradeoff-and-failure